Medidas para o controle da aflatoxina B1: uma breve revisão sobre o uso de flavonoides e argilas

Autores

  • Janaína Nones Universidade Federal de Santa Catarina
  • Humberto Gracher Riella Universidade Federal de Santa Catarina
  • Jader Nones Universidade Federal de Santa Catarina

DOI:

https://doi.org/10.5007/2175-7925.2017v30n1p1

Palavras-chave:

Aflatoxina B1, Argila, Flavonoides, Mecanismo de ação

Resumo

A aflatoxina B1 (AFB1) é uma das micotoxinas mais abundantes e tóxicas produzidas por cepas toxigênicas. Esta substância afeta a viabilidade celular, sendo capaz de induzir a morte, tanto de células humanas, quanto de células animais. Medidas vêm sendo adotadas para minimizar os danos causados pela AFB1, incluindo a utilização de flavonoides (compostos polifenólicos extraídos de plantas) e bentonitas (um tipo de argila). Nesta revisão, as características físico-químicas da AFB1 e seus efeitos em diferentes tipos de células, in vitro e in vivo, foram abordados. Além disso, a capacidade de proteção celular a partir de substâncias e materiais naturais, tais como flavonoides e bentonita, foi brevemente descrita. Também relatamos os efeitos econômicos causados pelas micotoxinas e sugerimos alternativas (flavonoides e bentonita) para novas abordagens terapêuticas visando combater a toxicidade causada por estas substâncias (AFB1).

Biografia do Autor

Janaína Nones, Universidade Federal de Santa Catarina

Possui doutorado (2016) em Engenharia Química (UFSC), mestrado (2012) em Ciência dos Alimentos (UFSC) e graduação em Química (UFSC), sendo portadora dos graus de Bacharel (2010) e Licenciatura (2010). Tem experiência na área de Química, Engenharia Química e Engenharia de Alimentos, com ênfase no desenvolvimento e caracterização de novos materiais e uso de técnicas analíticas para detecção e quantificação de substâncias tóxicas.

Humberto Gracher Riella, Universidade Federal de Santa Catarina

Graduado em Engenharia Química pela Universidade Federal do Paraná (1975), Mestrado em Tecnologia Nuclear pela Universidade de São Paulo (1978) e Doutorado em Maschinenbauingenier - Karlsruher Institut für Technologie (1983). Professor Titular Classe da Universidade Federal de Santa Catarina e do Programa de Pós-Graduação em Engenharia Química. Atua, principalmente, nos seguintes temas: Combustíveis Nucleares, Resíduos Sólidos Industriais, Processamento de Minerais metálicos, Materiais Antimicrobianos, Síntese de Materiais Nanoestruturados e Técnicas de Caracterização de Materiais.

Jader Nones, Universidade Federal de Santa Catarina

Atualmente é Professor voluntário do Departamento de Biologia Celular, Citologia e Genética da Universidade Federal de Santa Catarina (UFSC) e coordenador do Programa Estadual de Sanidade Suídea na Companhia Integrada de Desenvolvimento Agrícola de Santa Catarina (CIDASC). Realizou pós-doutorado (2012) em Biologia Celular e do Desenvolvimento pela UFSC, doutorado e mestrado em Ciências Morfológicas (2011 e 2008, respectivamente) pela Universidade Federal do Rio de Janeiro (UFRJ). Graduou-se em Medicina Veterinária pela Universidade do Estado de Santa Catarina - UDESC (2006) e Técnico em Agropecuária pela Escola Agrotécnica Federal de Rio do Sul (2002). Trabalhou na Empresa de Pesquisa Agropecuária e Extensão Rural (Epagri), exercendo a função de extensionista rural (2009/2010). Tem experiência em defesa sanitária animal e morfologia, com ênfase em histologia, fisiologia e embriologia.

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