Aprimoramento cognitivo: técnicas e controvérsias
DOI:
https://doi.org/10.5007/1677-2954.2021.e79915Palabras clave:
Trabalho, Educação, Democracia, Descentralização, Participação, Labor, Education, Democracy, Decentralization, ParticipationResumen
O objetivo deste artigo é apresentar o estado da arte das pesquisas científicas sobre aprimoramento cognitivo, visando a fornecer subsídios para uma discussão menos especulativa sobre o tema. Para tal, realizamos uma revisão integrativa da literatura sobre os dispositivos de aprimoramento cognitivo biotecnológicos vigentes. O resultado aponta para o caráter inconcluso das pesquisas, não havendo respostas significativas que certifiquem a efetividade de práticas de aprimoramento cognitivo, ao menos da forma como este vem sendo idealizado e discutido. Defenderemos, assim, que os investimentos na área precisam ser analisados sob o ponto de vista da justiça, levando-se em consideração outras formas de aprimoramento cognitivo disponíveis e comprovadas. Pretendemos indicar como alternativa um investimento substancial na mais antiga forma de aprimoramento humano, a educação, a fim de que novas metodologias possam ser pensadas e adequadas às demandas da sociedade contemporânea e a um ideal de sociedade mais justa e igualitária.
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AIKINS, Ross. The White Version of Cheating? Ethical and social equity concerns of cognitive enhancing drug users in higher education. Journal of academic ethics, v. 17, n. 2, p. 111-130, 2019.
ALTHEN, Heike et al. Effects of transcranial direct current stimulation of the frontopolar cortex on analogical reasoning performance. European Neuropsychopharmacology, v. 29, p. S559, 2019.
BATISTELA, Silmara et al. Methylphenidate as a cognitive enhancer in healthy young people. Dementia & Neuropsychologia, v. 10, n. 2, p. 134-142, 2016.
BEAR, Mark F.; CONNORS, Barry W.; PARADISO, Michael A. Neurociências: desvendando o sistema nervoso. Porto Alegre: Artmed, 2008.
BERGER, Theodore W. et al. A cortical neural prosthesis for restoring and enhancing memory. Journal of Neural Engineering, v. 8, n. 4, p. 046017, 2011.
BEYNEL, Lysianne et al. Effects of online repetitive transcranial magnetic stimulation (rTMS) on cognitive processing: A meta-analysis and recommendations for future studies. Neuroscience & Biobehavioral Reviews, v. 107, p. 47-58, 2019.
BLANK, Robert H. Regulating Cognitive Enhancement Technologies: Policy Options and Problems. In: JOTTERAND, Fabrice; DUBLJEVIĆ, Veljko (Eds.). Cognitive Enhancement: Ethical and Policy Implications in International Perspectives. Oxford: Oxford University Press, p. 239-258, 2016.
BOZKURT, Aras. From distance education to open and distance learning: A holistic evaluation of history, definitions, and theories. In: Handbook of research on learning in the age of transhumanism. New York: IGI Global, 2019, p. 252-273.
CAVIOLA, Lucius; FABER, Nadira S. Pills or push-ups? Effectiveness and public perception of pharmacological and non-pharmacological cognitive enhancement. Frontiers in psychology, v. 6, p. 1852, 2015.
CUTSURIDIS, Vassilis. Memory prosthesis: is it time for a deep neuromimetic computing Approach? Frontiers in Neuroscience, v. 13, 2019.
DE ANGELIS, Oliver J. The effect of modafinil on behavioural and ERP correlates of inhibitory control in healthy, non-sleep deprived individuals, 2016. Report for degree of Bachelor of Psychology, University of Tasmania.
DI LAZZARO, Vincenzo et al. Modulation of motor cortex neuronal networks by rTMS: comparison of local and remote effects of six different protocols of stimulation. Journal of neurophysiology, v. 105, n. 5, p. 2150-2156, 2011.
DI LAZZARO, Vincenzo; ZIEMANN, Ulf. The contribution of transcranial magnetic stimulation in the functional evaluation of microcircuits in human motor cortex. Frontiers in neural circuits, v. 7, p. 18, 2013.
DI PINO, Giovanni et al. Augmentation-related brain plasticity. Frontiers in systems neuroscience, v. 8, p. 109, 2014.
DIAS, Maria Clara. A perspectiva dos funcionamentos: por uma abordagem moral mais inclusiva. Rio de Janeiro: Pirilampo, 2015.
DIAS, Maria C. Sobre nós: expandindo as fronteiras da moralidade. Rio de Janeiro: Pirilampo, 2016.
DIMPFEL, Wilfried; STORNI, Charlotte; VERBRUGGEN, Marian. Ingested oat herb extract (Avena sativa) changes EEG spectral frequencies in healthy subjects. The Journal of Alternative and Complementary Medicine, v. 17, n. 5, p. 427-434, 2011.
DINH, Claire T.; HUMPHRIES, Stacey; CHATTERJEE, Anjan. Public Opinion on Cognitive Enhancement Varies across Different Situations. AJOB Neuroscience, v. 11, issue 4, p. 224-237, 2020.
DEADWYLER, Sam A. et al. A cognitive prosthesis for memory facilitation by closed-loop functional ensemble stimulation of hippocampal neurons in primate brain. Experimental Neurology, v. 287, p. 452-460, 2017.
DOMÍNGUEZ, Miriam B. Potenciadores cognitivos:¿Realidad o ficción? Medicentro Electrónica, v. 22, n. 2, p. 108-115, 2018.
DUTTA, Lopamudra et al. Lipid-based nanocarrier efficiently delivers highly water soluble drug across the blood–brain barrier into brain. Drug Delivery, v. 25, n. 1, p. 504-516, 2018.
ESPOSITO, Roberto et al. Acute effects of modafinil on brain resting state networks in young healthy subjects. PLoS One, v. 8, n. 7, p. e69224, 2013.
FINGER, Guilherme S. E. R.; FALAVIGNA, Asdrubal. Use of methylphenidate among medical students: a systematic review. Revista da Associação Médica Brasileira, v. 59, n. 3, p. 285-289, 2013.
FRANKE, Andreas G. et al. Use of illicit and prescription drugs for cognitive or mood enhancement among surgeons. BMC medicine, v. 11 (102), n. 1, p. 1-9, 2013.
FRANKE, Andreas G.; NORTHOFF, Robert; HILDT, Elisabeth. The case of pharmacological neuroenhancement: medical, judicial and ethical aspects from a german perspective. Pharmacopsychiatry, v. 48, n. 07, p. 256-264, 2015.
FREESE, Luana et al. Non-medical use of methylphenidate: a review. Trends in Psychiatry and Psychotherapy, v. 34, n. 2, p. 110-115, 2012.
FROESTL, Wolfgang; MUHS, Andreas; PFEIFER, Andrea. Cognitive enhancers (nootropics). Part 1: drugs interacting with receptors. Journal of Alzheimer's disease, v. 32, n. 4, p. 793-887, 2012.
FROESTL, Wolfgang; MUHS, Andreas; PFEIFER, Andrea. Cognitive enhancers (nootropics). Part 2: Drugs interacting with enzymes. Journal of Alzheimer's Disease, v. 33, n. 3, p. 547-658, 2013.
FROESTL, Wolfgang; MUHS, Andreas; PFEIFER, Andrea. Cognitive enhancers (nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. Journal of Alzheimer's Disease, v. 34, n. 1, p. 1-114, 2013.
GENG, JinSong et al. Ginseng for cognition. Cochrane Database of Systematic Reviews, n. 12, 2010.
GLADDEN, Matthew E. Neuroprosthetic supersystems architecture: considerations for the design and management of neurocybernetically augmented organizations. Synthypnion Academic, 2017a.
GLADDEN, Matthew E. The Handbook of information security for advanced neuroprosthetics. Synthypnion Academic, 2017b.
GOEL, Bharti; MAURYA, Neelesh K. Memory booster herb (natural cognitive enhancers): An overview. International Journal of Physiology, Nutrition and Physical Education, v. 4, n. 1, p. 975-979, 2019.
GOKSEL, Nil; BOZKURT, Aras. Artificial intelligence in education: Current insights and future perspectives. In: Handbook of research on learning in the age of transhumanism. IGI Global, 2019, p. 224-236.
HALLETT, Mark. Transcranial magnetic stimulation: a primer. Neuron, v. 55, n. 2, p. 187-199, 2007.
HAMPSON, R. E. et al. Extraction and restoration of hippocampal spatial memories with non-linear dynamical modeling. IEEE Transactions on Neural Systems and Rehabilitation Engineering, v. 20, p. 184-197, 2012.
HILDT, Elisabeth; LIEB, Klaus; FRANKE, Andreas Günter. Life context of pharmacological academic performance enhancement among university students–a qualitative approach. BMC Medical Ethics, v. 15, n. 1, p. 1-10, 2014.
HUPLI, Aleksi. Cognitive enhancement with licit and illicit stimulants in the Netherlands and Finland: what is the evidence? Drugs and Alcohol Today, v. 20, n. 1, 2020.
HYSEK, Cédric M. et al. Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination. International journal of neuropsychopharmacology, v. 17, n. 3, p. 371-381, 2014.
JENSEN, Sean R. et al. SIENNA D3.1: State-of-the-art Review: Human Enhancement. SIENNA Project, 2018. Disponível em: https://zenodo.org/record/4066557#.YCkpnGhKhPY. Acesso em: 14 fev. 2021.
KAHATHUDUWA, Chanaka N. et al. Acute effects of theanine, caffeine and theanine–caffeine combination on attention. Nutritional Neuroscience, v. 20, n. 6, p. 369-377, 2017.
KIM, Binna et al. A review of fermented foods with beneficial effects on brain and cognitive function. Preventive nutrition and food science, v. 21, n. 4, p. 297, 2016.
LENT, Roberto. Cem bilhões de neurônios: conceitos fundamentais de neurociência. Rio de Janeiro: Atheneu, 2010.
LUBER, Bruce. Neuroenhancement by noninvasive brain stimulation is not a net zero-sum proposition. Frontiers in systems neuroscience, v. 8, p. 127, 2014.
LUBER, Bruce; LISANBY, Sarah H. Enhancement of human cognitive performance using transcranial magnetic stimulation (TMS). Neuroimage, v. 85, p. 961-970, 2014.
LUGER, George F. Inteligência artificial: estruturas e estratégias para a solução de problemas complexos. Porto Alegre: Bookman, 2004.
LUQUE-CASADO, Antonio et al. Exploring the effects of transcranial direct current stimulation over the prefrontal cortex on working memory: a cluster analysis approach. Behavioural Brain Research, v. 375, p. 112144, 2019.
MAIA, Igor F. Disputas em torno da Ritalina: uma análise sobre diferentes possibilidades de um fármaco. 2017. 136 f. Dissertação de Mestrado em Ciências Sociais – Programa de Pós-graduação em Ciências Sociais, Universidade Federal do Rio Grande do Norte, Natal, 2017.
MACHADO, Sergio et al. Interface cérebro-computador: novas perspectivas para a reabilitação. Revista Neurociências, v. 17, n. 4, p. 329-235, 2009.
MANCUSO, Lauren E. et al. Does transcranial direct current stimulation improve healthy working memory? A meta-analytic review. Journal of Cognitive Neuroscience, v. 28, n. 8, p. 1063-1089, 2016.
MITTAL, Deepti et al. Brain targeted nanoparticulate drug delivery system of rasagiline via intranasal route. Drug Delivery, v. 23, n. 1, p. 130-139, 2016.
MIRANDA, Ana A. A. Aplicações da nanotecnologia em doenças do foro neurológico: vantagens e desafios. Boletim Informativo Geum, v.5, n.4, p.14–30, out./dez., 2014.
MOHAMED, Ahmed D.; LEWIS, Chris R. Modafinil increases the latency of response in the Hayling Sentence Completion Test in healthy volunteers: a randomised controlled trial. PLoS One, v. 9, n. 11, p. e110639, 2014.
MONTEIRO, Brisa M. M. et al. Metilfenidato e melhoramento cognitivo em universitários. SMAD Revista Eletrônica Saúde Mental Álcool e Drogas, v. 13, n. 4, p. 232-242, 2017.
MORALES-QUEZADA, Leon et al. Cognitive effects and autonomic responses to transcranial pulsed current stimulation. Experimental Brain Research, v. 233, n. 3, p. 701-709, 2015.
MÜLLER, Ulrich et al. Effects of modafinil on non-verbal cognition, task enjoyment and creative thinking in healthy volunteers. Neuropharmacology, v. 64, p. 490-495, 2013.
NASCIMENTO, José L. M.; BASTOS, Gilmara N. T. Psicofármacos para aprimoramento das funções cognitivas. Neuro, p. 147, 2013.
OUTRAM, Simon M. The use of methylphenidate among students: the future of enhancement? Journal of Medical Ethics, v. 36, n. 4. pp. 198-202, 2010.
PARK, Jeongmin et al. Nootropic nanocomplex with enhanced blood-brain barrier permeability for treatment of traumatic brain injury-associated neurodegeneration. Journal of Controlled Release, v. 284, p. 152-159, 2018.
PARTRIDGE, Bradley J. et al. Smart drugs “as common as coffee”: media hype about neuroenhancement. PloS one, v. 6, n. 11, p. e28416, 2011.
PRODANOV, Dimiter; DELBEKE, Jean. Mechanical and biological interactions of implants with the brain and their impact on implant design. Frontiers in Neuroscience, v. 10, p. 11, 2016.
RICCI, Giovanna. Pharmacological human enhancement: an overview of the looming bioethical and regulatory challenges. Frontiers in Psychiatry, v. 11, p. 53, 2020.
SCHMIDT, André et al. Acute effects of methylphenidate, modafinil, and MDMA on negative emotion processing. International Journal of Neuropsychopharmacology, v. 21, n. 4, p. 345-354, 2018.
SCHUTTER, Dennis J. L. G.; WISCHNEWSKI, Miles. A meta-analytic study of exogenous oscillatory electric potentials in neuroenhancement. Neuropsychologia, v. 86, p. 110-118, 2016.
VAN DER SCHAAF, Marieke E. et al. Dopaminergic drug effects during reversal learning depend on anatomical connections between the orbitofrontal cortex and the amygdala. Frontiers in Neuroscience, 7, 142, 2013.
WOŹNIAK-KWAŚNIEWSKA, Agata et al. Changes of oscillatory brain activity induced by repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex in healthy subjects. Neuroimage, v. 88, p. 91-99, 2014.
YAMAMOTO, Midori; ISHII, Yuji. Awareness survey of smart drugs among undergraduates. Iyakuhin Johogaku, v. 20, n. 1, p. 41-46, 2018.
YAWALKAR, Mr. Vivek V. A study of artificial intelligence and its role in human resource management. International Journal of Research and Analytical Reviews (IJRAR), p. 20-24, 2019.
ZHANG, Yujie; GRUBER, Reut. Focus: Attention science: can slow-wave sleep enhancement improve memory? A review of current approaches and cognitive Outcomes. The Yale Journal of Biology and Medicine, v. 92, n. 1, p. 63, 2019.
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